Biomarker Core Lab

Mission

To provide biomarker data in a cost-, and effort-efficient manner to bio/psycho/social researchers who do not do these assays on a regular basis.

Facilities Statement

The Biomarker Core Lab (BCL) is a 1,200-ft. laboratory in the department of Biobehavioral Health at Penn State University providing biomarker research support and training as well as fee-for service testing for PSU faculty and their collaborators and students. The fee-for-service menu includes complete sample analysis, sample organization, sample aliquoting, long-term sample storage and independent use of lab equipment. Types of samples routinely processed include saliva, serum, plasma, hair and dried bloodspots. Available and currently in-use equipment includes: BioTek Synergy plate reader, BioTek plate washer, two multi-plex platforms: MesoScale Discovery Quick-Plex & BioRad Bioplex 200, precision analytical balances, single & multi-channel pipettes, centrifuges, refrigerators and freezers. Some of the biomarkers tested for are:

  • Cytokines, to measure immune function
  • Cortisol, to measure physiological stress

The lab is a part of the Department of Biobehavioral Health serving the entire Penn State community, including Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, and Penn State Hershey Children's Hospital.

Who We Serve

  • Penn State researchers (students and faculty) who lack laboratory equipment, skills or time to conduct their own testing.
  • Faculty and students within the university where laboratory space and equipment is not available.
  • Outside collaborators (co-PI’s) of Penn State faculty.

What We Do

  • Aliquotting and organization of samples for bioassays
  • Testing by ELISA (Enzyme-Linked Immunosorbant Assays) of biomarkers such as cortisol, cytokines, etc.
  • Advising on interpretation of our assay results

Assays Done by Other Core facilities at Penn State

Genotyping and sequencing – Genomics Core Facility

Mass spectroscopy – Metabolomics Facility

CLIA certified assays – Endocrine Core Laboratory at the College of Medicine (Hershey)

Contact us

Mary Curran

BCL Manager

146 Health and Human Development Building

mjc25@psu.edu

814-865-5559

Sheree F. Logue, Ph.D.

BCL Director

113 Biobehavioral Health Bldg

sul459@psu.edu

814-863-2472

Please remember to acknowledge our work in any publication that uses data from the BCL – it is an important metric for our evaluation. Example: We thank the Biomarker Core Laboratory in the Department of Biobehavioral Health, Penn State for biological assay data.